How Humidity Control Impacts Pharmaceutical Product Shelf Life
How Humidity Control Impacts Pharmaceutical Product Shelf Life A batch of soft gelatin capsules comes off the line looking perfect. Three weeks later, during a routine stability check, someone notices the capsules have gone slightly tacky. Nothing dramatic — no visible mold, no obvious defect — but enough that the QA team has to ask an uncomfortable question: what happened between manufacturing and now? More often than not, the answer is moisture. Not a leak, not contamination in the traditional sense — just humidity that crept a few percentage points outside where it should have been, at some point in the product's journey from mixing room to warehouse shelf. It's an easy thing to overlook because humidity doesn't announce itself the way temperature does. A facility can be running its air conditioning perfectly and still have relative humidity drifting well outside safe limits, because cooling the air and drying the air are two different jobs. Pharmaceutical products —...
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